Pomegranates Fuel Tumor-Fighting Cells

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Pomegranates Fuel Tumor-Fighting Cells

Urolithin A, a metabolite of ellagitannins in pomegranates, boosts immune cells’ ability to combat tumors by inducing a process known as mitophagy.
STORY AT-A-GLANCE

Urolithin A (UA) has emerged as a powerhouse player in the fight against cancer, as it may naturally boost tumor-fighting immune cells
UA is a metabolite of ellagitannins in pomegranates that has anti-inflammatory and anticancer effects
UA "recycles and renews mitochondria" by inducing a biological pathway known as mitophagy — the process of cleaning out your mitochondria, allowing them to function at their best
This changes T cells' genetic program, making them more able to fight tumors
In an upcoming clinical trial, UA will be used in people with colorectal cancer to determine its effectiveness

Globally, colorectal cancer is the third most-diagnosed cancer, with a high mortality rate in its advanced stages. One reason for its lethal effects is the ability of tissue around the tumor — or the tumor microenvironment — to suppress tumor-fighting immune cells. With the body's immune T cells restricted, the tumor is able to grow and spread.[1]...

Source: Pomegranates Fuel Tumor-Fighting Cells

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