Classifieds

Neuropathic pain is a disorder characterized by abnormal pain perception, which can cause extreme pain to even mild stimuli and bring great discomfort to daily life. Now, the cells needed for natural recovery from pain have been identified in a Japanese study.
In April, a research project led by Professor Makoto Tsuda and Takahiro Masuda, an associate professor at the Graduate School of Pharmaceutical Sciences, Kyushu University, identified the cells needed for natural recovery from pain. The results were published in the journal Science in March.
The researchers found that some activated microglia in the spinal cord of mice with nerve injury changed and began to form a specialized subset. The timing of these changes correlated with the duration of pain reduction. The researchers proved the role of this microglial subset by removing it from the spinal cords of mice. After the removal, they observed that the pain did not naturally subside and persisted for a long time....