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For people with a type of chronic pain called trigeminal neuralgia, touch from everyday activities like face-washing, eating, or tooth-brushing can cause agonizing pain that can be hard to treat. Trigeminal neuralgia is a type of neuropathic pain, which is caused by damaged or irritated nerves. In this case, pain arises from insults to the trigeminal nerve, which carries sensations from the head, face, and oral cavity to the brain. Trigeminal nerves can be injured by a blood vessel pressing on the nerve, surgery, or diseases such as multiple sclerosis. A more complete understanding of the cellular and molecular basis of trigeminal neuralgia could help scientists find treatments that bring better relief to patients....